Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-03-26
1992-04-21
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514256, 514338, 544333, 546271, 548329, A61K 31415, C07D23504
Patent
active
051068630
ABSTRACT:
Novel substituted imidazole and pyridine derivatives and their synthesis are disclosed. The derivatives inhibit the enzyme, H.sup.+ /K.sup.+ ATPase, and are therefore useful for the treatment of gastrointestinal diseases.
REFERENCES:
patent: 3558775 (1971-01-01), Fournier
Cecil Medical Textbook Saunders Co. p. 598 (1983).
Lacova et al. "2-2,4-dinitrophenylthio . . . ", CA 92: 216176n (1982).
Bianchi et al. "Compounds with Antiulcer . . . ", CA 95: 203828k (1981).
Noyanalpan et al. "Synthesis of Some-2-(Heterocyclic . . . ", CA 101: 90831c (1984).
Paglietti et al. "2-aryl-S-benzimidazoles . . . " CA 101: 90825.
Aries et al. "Insecticidal Compositions . . . ", CA 78:39352b (1973).
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Hajos Zoltan G.
Press Jeffery B.
Roberts Jerry R.
Chang Celia
Ivy C. Warren
Lambert Benjamin F.
Ortho Pharmaceutical Corporation
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