Sensitized matrix for detection of disease

Details Sensitized matrix for detection of disease Sensitized matrix for detection of disease

1974-11-11

1976-04-20

Monacell, A. Louis

Textiles: fiber preparation

424 12, 23230B, C12K 104

Patent

active

039517489

ABSTRACT:
A specific sensitized matrix for diagnosing both infectious and non-infectious disease is disclosed comprised of an insoluble, inert, pliable and wettable matrix having a network of pores, and a protein polymer network immobilized in the network of pores formed of protein carrier molecules, specific antigens or antibodies, and a coupling agent coupling the protein carrier molecules together and the antigen or antibody to the protein carrier molecules. A variety of matrix materials, protein carrier molecules, specific antigens or antibodies and coupling agents can be used. Methods of preparing the sensitized matrix and diagnostic test procedures utilizing the sensitized matrix for detecting disease are also disclosed.

REFERENCES:
patent: 3791932 (1974-02-01), Schuurs et al.
Silman et al., "Water-Insoluble Derivatives of Enzymes, Antigens, and Antibodies", Annual Review of Biochemistry, Vol. 35, pt. II, 1966, pp. 873-880.

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