Method for the production of nuclear substituted cinnamoylanthra

Details Method for the production of nuclear substituted cinnamoylanthra Method for the production of nuclear substituted cinnamoylanthra

1984-02-07

1984-12-04

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 9900

Patent

active

044865970

ABSTRACT:
The present invention provides an improved method for producing a nuclear substituted cinnamoylanthranilic acid compound.
Illustrative of the process is the reaction of 3,4-dimethoxybenzaldehyde with 2-carboxymalonanilic acid in an inert solvent medium in the presence of piperidine to provide an intermediate salt precipitate, and the salt is treated with an acidic reagent to yield N-(3,4-dimethoxycinnamoyl)anthranilic acid product.

REFERENCES:
patent: 3755603 (1973-08-01), Harrison et al.
patent: 4337270 (1982-06-01), Noda et al.

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