Heterocyclic compounds and their preparation and use

Details Heterocyclic compounds and their preparation and use Heterocyclic compounds and their preparation and use

1988-02-16

1989-12-26

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544344, 544345, 544354, 546171, 560 44, 558424, C07D48704, C07D24144, A61K 31495

Patent

active

048898554

ABSTRACT:
Heterocyclic dihydroxyquinoxaline compounds having the formula ##STR1## wherein --A-- together with the two carbon atoms denoted as 1 and 2 is selected from ##STR2## R.sup.1, R.sup.2 and R.sup.3 are independently H, halogen, CN, NH.sub.2, NO.sub.2, SO.sub.3 H, SO.sub.2 NH.sub.2, or CONH.sub.2
The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use.
The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters.

REFERENCES:
patent: 3431111 (1969-03-01), Brooker
Yamatani I, Chem Abs 74, 3658j (1967).
Yamatani II, Chem Abs 73, 131031r (1967).
Goodmar et al, "The Pharmacological Basis of Therapeutics", pp. 1657-1658.

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