Dry analytical element having a spread control area for assaying

Details Dry analytical element having a spread control area for assaying Dry analytical element having a spread control area for assaying

1987-05-26

1989-12-26

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435291, 435805, 435810, 422 56, 422 57, 422 58, 422 60, 422 61, 422 68, 436808, 436810, C12Q 100, C12Q 148, G01N 3350, G01N 3090

Patent

active

048897973

ABSTRACT:
A dry analytical element for assaying an enzyme in a liquid is disclosed, comprising a support having provided thereon at least a porous liquid-spreading layer composed of water non-absorbent fibers, wherein said porous liquid-spreading layer contains a substrate for an enzyme to be assayed and a hydrophilic polymer in an amount effective to decrease a spreading area by at least 20%. The analytical element exhibits high sensitivity and high reproducibility.

REFERENCES:
patent: 3867258 (1975-02-01), Forgione
patent: 3992158 (1976-11-01), Przybylowicz et al.
patent: 4258001 (1981-03-01), Pierce et al.
patent: 4275031 (1981-06-01), Fischer et al.
patent: 4486537 (1984-12-01), Koyama et al.
patent: 4615983 (1986-10-01), Koyama et al.
D'Souza et al, "Multilaboratory Evaluation of Six Enzyme Tests on the Kodak Ektachem 700 Analyzer", (poster session XII International Congress of Clinical Chemistry), 1984.

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