Sulfonic resins having a therapeutical activity, preparation the

Details Sulfonic resins having a therapeutical activity, preparation the Sulfonic resins having a therapeutical activity, preparation the

Filed on

1985-03-07

Date issued

1986-05-06

Examiner

Bond, Robert T.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

2602393B, A61K 3155, C07D28110

Type

Patent

Status

active

Patent number

045872422

Description

ABSTRACT:
A pharmaceutical compound characterized by a delayed release of the therapeutically active component, comprising a sulfonic type ion exchange resin and cis(.+-.)-3-acetyloxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyp henyl)-1,5-benzothiazepin-4(5H)one, or cis(.+-.)-3-hydroxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphe nyl)-1,5-benzothiazepin-4(5H)one as a therapeutically active compound.
A process for the preparation of the active compound.
A pharmaceutical composition including said active compound, and use of said composition for the prophylaxis and therapy of acute and chronical coronary insufficiency and of arterial hypertension.

REFERENCES:
patent: 3562257 (1971-02-01), Kugita et al.
patent: 3646008 (1972-02-01), Kugita et al.

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