Chemistry: analytical and immunological testing – Thyroid hormone tests
Patent
1983-12-30
1986-05-06
Nucker, Christine M.
Chemistry: analytical and immunological testing
Thyroid hormone tests
436510, 436536, 436537, 436538, 436542, 436800, 436804, 436808, 436809, 436814, 436817, 436824, 422 56, 422 57, 422 58, 422 59, 422 68, 210780, 210799, 210359, G01N 3353, G01N 33536, G01N 33537, B01D 3300
Patent
active
045872210
ABSTRACT:
The present invention relates to a method which eliminates centrifugation and decantation steps, to be performed in an automatic manner for carrying out specific binding assay tests, wherein liquid and solid phases are present.
According to the invention, use is made of a specially designed device, consisting of a mixing reservoir into which is fitted snugly a mixer separator having a channel in the vertical axis of the mixer-separator. A rack holding a number of said mixing reservoirs containing the incubated reagents and analytes, capped with the mixer separators, is placed into a press-device designed to perform at a controlled rate a downward movement. The mixer separators are pushed downwards into the mixing reservoirs at a chosen rate for a preselected distance to complete the mass transport and separation operations. The separation devices are removed and either one of the separated phases can be measured in the desired analytical instrument for a quantitative or qualitative determination.
The results obtained according to the present invention compare very favorably with those determined by other methods requiring centrifugation and/or decantation in the assay protocol.
REFERENCES:
patent: 2524362 (1950-10-01), Smith
patent: 3068855 (1962-12-01), Furlong, Jr.
patent: 3449081 (1969-06-01), Hughes
patent: 3969250 (1976-07-01), Farr
patent: 3992150 (1976-11-01), Retzer
patent: 4021352 (1977-05-01), Sarstedt
patent: 4071319 (1978-01-01), Nugent
patent: 4087248 (1978-05-01), Miles
patent: 4197287 (1980-04-01), Piasio et al.
patent: 4235865 (1980-11-01), Thoma
patent: 4254082 (1981-03-01), Schick et al.
Cais Michael
Shimoni Moshe
Nucker Christine M.
Technion Research & Development Foundation Ltd.
LandOfFree
Non-centrifugation method for immunoassay of materials does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Non-centrifugation method for immunoassay of materials, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Non-centrifugation method for immunoassay of materials will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1574590