Process for synthesizing chromanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D31170

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049580353

ABSTRACT:
The present invention is directed to a novel process for producing chromane derivatives, which are suitable as intermediates for the manufacture of d-.alpha.-tocopherol (natural vitamin E), and with a process for producing d-.alpha.-tocopherol itself.

REFERENCES:
Kitamura, J. Am Chem Soc. 108, 6071-6072, (1986).
Houben-Weyl, Meth. Der Organ. Chemie, Bd. XIII/2a, pp. 592-601.
Gray, J. Org. Chem. 49, 2288 (1984).
Barner, Helv, Chemica Acta 62, Fasc. 7 (1979).
L. J. Smith, Am. Chem. Soc. 59, 673 (1937).
McCormick et al., Methods in Enzymology, vol. VIII, Vitamins and Coeyzymes Park C. (1971). pp. 272-273.

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