Therapeutic valine esters of acyclovir and pharmaceutically acce

Details Therapeutic valine esters of acyclovir and pharmaceutically acce Therapeutic valine esters of acyclovir and pharmaceutically acce

1988-08-04

1990-09-18

Rivers, Diana G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544276, A61K 3152, C07D47316

Patent

active

049579240

ABSTRACT:
The present invention relates to certain amino acid exters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment of herpes virus infections. The invention also includes pharmaceutical formulations and processes for the preparation of such compounds.

REFERENCES:
patent: 4199574 (1980-04-01), Schaeffer
patent: 4287188 (1981-09-01), Schaeffer
patent: 4294831 (1981-10-01), Schaeffer
patent: 4457919 (1984-07-01), Simon et al.
patent: 4548819 (1985-10-01), De Clercq et al.
patent: 4567182 (1986-01-01), Ferraris
patent: 4695570 (1987-09-01), Krenitsky
patent: 4745119 (1988-05-01), Krenitsky

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