Production of cyclopentenones by enzyme resolution

Details Production of cyclopentenones by enzyme resolution Production of cyclopentenones by enzyme resolution

1987-05-29

1990-09-18

Rosen, Sam

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435135, 435136, 435149, C12P 762, C12P 738

Patent

active

049578677

ABSTRACT:
A process for preparing an optically active cyclopentenone of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group and n is an integer of 4 to 8, which comprises contacting a dl-cyclopentenone ester of the formula: ##STR2## wherein R and n are each as defined above and R' is a lower alkyl group optionally substituted with halogen on an enzyme having a capability of hydrolyzing selectively either one of the d- or l-form isomer in the dl-cyclopentenone ester (II) in an aqueous medium for asymmetric hydrolysis.

REFERENCES:
patent: 3892630 (1975-07-01), Kurozumi et al.
patent: 4511655 (1985-04-01), Minai et al.
patent: 4607013 (1986-08-01), Matsuda et al.
patent: 4729953 (1988-03-01), Minai et al.
Miura et al, -Chem. Abst., vol. 89 (1978), pp. 105, 910n.
Chemical Abstracts, vol. 105, No. 19, Nov. 10, 1986, Abstract No. 170,652t.
Chemical Abstracts, vol. 102, No. 3, Jan. 21, 1985, Abstract No. 22,826a.
Chemical Abstracts, vol. 105, No. 19, Nov. 10, 1986, Abstract No. 168,493y.
Chemical Abstracts, vol. 105, No. 19, Nov. 10, 1986, Abstract No. 170,645t.
Chemical Abstracts, vol. 103, No. 15, Oct. 14, 1985, Abstract No. 121,764f.

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