Thromboxane synthase inhibitors as antiobesity agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514355, 514909, A61K 3144

Patent

active

045915946

ABSTRACT:
The present disclosure relates to the use of thromboxane synthase inhibitors as antiobesity agents and insulin lowering agents. Such compounds fall into a variety of classes among which are 1-substituted imidazoles, 4-substituted imidazoles, 3-substituted pyridines, 3-substituted indoles, 4-substituted pyrimidines, 5-substituted tetrazoles, pyrazolidines, quinazolines, and substituted xanthene carboxylic acids.

REFERENCES:
patent: 4098908 (1978-07-01), Kathawala
Chem. Abst. 66: 103339j (1967)--Silvestrini.
Chem. Abst. 67: 18261(d) (1967)--Chmielowa et al.
Chem. Abst. 70: 104,175x (1969)--Lackova et al.
Chem. Abst. 86: 104,296t (1977)--Badilescu et al.
Chem. Abst. 101: 66403n (1984)--Coppes et al.

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