Succinimidyl trityl compounds and a process for preparing same

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548215, 536 2531, C07D20740

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active

054100682

ABSTRACT:
The invention pertains to compounds and methods for the reversible modification of natural products, biopolymers or synthons for natural products or biopolymers, such as nucleosides, nucleotides, and oligonucleosides. The modification enables one to perform a variety of chemistries on these compounds, yet can be removed to regenerate functional groups on the natural products, biopolymer or synthon of interest.

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Seliger, V. H. and H.-G. Gortz; Angew. Chem. Int. Ed. Engl. 20:683-684 (1981).
Schmidt, G. et al., Nucleosides and Nucleotides 7:795-799 (1988).
Happ, E. and C. S. Happ, Nucleosides and Nucleotides, 7:813-816 (1988).
Kwiatkowski, M. and J. Chattopadhyaya, Acta. Chemi. Scan. B38:657-671 (1984).
Gildea, B. D. et al., Abstract from the American Assoc. of Clin. Chemistry, 4th San Diego Conference on Nucleic Acid Applications, San Diego, Calif. (Oct. 25-27, 1989).

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