Heteroaryl quinolines as inhibitors of leukotriene biosynthesis

Details Heteroaryl quinolines as inhibitors of leukotriene biosynthesis Heteroaryl quinolines as inhibitors of leukotriene biosynthesis

1993-07-20

1995-04-25

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546142, 546153, 546155, C07D21512, C07D21516, C07D21722, C07D21718

Patent

active

054100542

ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

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