Complexing urushiols

Details Complexing urushiols Complexing urushiols

1993-10-20

1995-04-25

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, A61K 31715

Patent

active

054099080

ABSTRACT:
This invention relates to use of cyclodextrins to complex urushiols to protect against and to treat irritation arising from exposure to urushiols. Cyclodextrins, particularly gamma-cyclodextrins, are capable of binding strongly to urushiols and can be used effectively to prevent irritation of tissue that is exposed to urushiols.
Cyclodextrin-urushiol complexes can also be used to desensitize against urushiol. Compositions containing cyclodextrin/urushiol complexes may be provided as tablets for buccal administration in dosages sufficient to induce desensitizing response.

REFERENCES:
patent: 3875301 (1975-04-01), Windheuser
patent: 4352794 (1982-10-01), Koch
patent: 4727064 (1988-02-01), Pitha
patent: 4808232 (1989-02-01), Beesley
patent: 5296472 (1994-03-01), Sanchez et al.

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