Electric heating apparatus for heat-treating pharmaceuticals

Electric heating – Heating devices – With heater-unit housing – casing – or support means

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Details

34 88, 128214A, 219220, 219354, 219405, 219411, 219415, 219418, 362 92, H05B 100, A61M 500, F24C 704

Patent

active

042739926

ABSTRACT:
An electric heating apparatus for preventing recrystallization or to dissolve existing crystals of pharmaceutical compositions, such as mannitol, which tend to recrystallize during storage. Single dose sealed vials of the pharmaceutical are received in a receptacle having an open top, closed bottom and reflective inner surfaces. A light bulb is supported in the receptacle above the vials and the radiant energy therefrom reflected from the inner surfaces of the receptacle heats the vials.
The light bulb and support therefor are of such dimension that visual observation of the vials through the open top is not obstructed. The support for the light bulb includes a swivel joint permitting horizontal movement of the light bulb to provide access to the interior of the receptacle for removal of the vials. The temperature within the receptacle is controlled by a control means, such as a thermostat, in circuit with the light bulb.

REFERENCES:
patent: 1444561 (1923-02-01), Schraeder
patent: 1630237 (1927-05-01), Smith
patent: 1912818 (1933-06-01), Becket
patent: 1945196 (1934-01-01), Kelley
patent: 2042855 (1936-06-01), Merklein
patent: 2057421 (1936-10-01), Dickson
patent: 2511643 (1950-06-01), Lawrence
"The Use of a Microwave Oven To Redissolve Crystallized Mannitol Injection (25%) in Ampuls", Michael L. Kleinberg, et al., Hospital Pharmacy, vol. 14, Jul. 1979, pp. 391, 392.
"Microwave Oven Explosion", Hospital Pharmacy, vol. 14, Oct. 1979, p. 612.
"Warming Kettle For Storing Mannitol Injection", Scott, et al., American Journal of Hospital Pharmacy, vol. 37, No. 1, Jan. 1980, pp. 16, 19 and 24.

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