Foam cell drug delivery

Details Foam cell drug delivery Foam cell drug delivery

1993-04-20

1995-04-25

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424450, 424 931, 4352401, A61K 914, A61K 9127

Patent

active

054097100

ABSTRACT:
Methods and pharmaceutical compositions for delivering a clinically relevant agent to a mammalian recipient in vivo are provided. The methods involve forming a foam cell from an isolated foam cell precursor in vitro, incorporating an agent into the foam cell, and administering the foam cell containing the agent to the mammalian recipient. In a preferred embodiment, the foam cell precursors are isolated from a human recipient, treated, and returned to the patient in the form of a foam cell containing a therapeutically effective amount of the agent.

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