Radiofrequency plasma treated polymeric surfaces having immobili

Details Radiofrequency plasma treated polymeric surfaces having immobili Radiofrequency plasma treated polymeric surfaces having immobili

1993-11-22

1995-04-25

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424422, 424423, 427535, 427536, 427539, 427238, 525 541, 525 542, 525406, 525423, 525454, 525474, 525937, 604 96, 604239, 21050024, 522915, A61L 3300, A61L 2900, A61K 31725, A61K 3562

Patent

active

054096960

ABSTRACT:
Polymeric surfaces of medical devices or components of medical devices are provided that have enhanced biocompatibility properties. The polymeric surface presents an anti-thrombogenic, fibrinolytic or thrombolytic interface with body fluids such as blood during implant ation or medical procedures. The biocompatibility enhancing agent is secured to the polymeric substrate by a spacer molecule which is covalently bound to the polymeric substrate which had been subjected to radiofrequency plasma treatment with a water vapor medium.

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