Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1992-10-19
1996-01-30
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 5, 435 912, 436501, 436811, 536 221, 536 231, 536 241, 536 243, 536 2431, 536 2432, 935 77, 935 78, C12Q 168
Patent
active
054879736
ABSTRACT:
A novel class of reagents for assaying nucleic acid sequences comprise successive layers of polynucleotides of a specific structure, including a double-stranded waist and single-stranded, free arms at the molecule ends, formed by hybridization of the arms to adjacent molecule arms. The reagent is used to assay for specific nucleic acid sequences. The outer layer of polynucleotides are specific for the sequence to be assayed through their non-annealed, free, single-stranded arms. The reagents are useful in the assay of a wide variety of nucleic acid sequences including those associated with pathogens such as pathogenic bacteria and virus.
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Nilsen Thor W.
Prensky Wolf
Evans Barry
Jones W. Gary
Marschel Ardin H.
Polyprobe, Inc.
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