Preparation of antithrombogenic polymeric materials

Details Preparation of antithrombogenic polymeric materials Preparation of antithrombogenic polymeric materials

1977-10-25

1981-06-16

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

3 1, 424 33, 424 78, 424 79, 424 94, 435181, 435215, C12N 1108, A61F 100

Patent

active

042738733

ABSTRACT:
Antithrombogenic polymeric materials are prepared by bonding a synthetic fibrinolytic compound or a combination of a synthetic fibrinolytic compound and a fibrinolytic enzyme to a polymeric material. Bonding is preferably by covalent or ionic bonding. The antithrombogenic polymeric materials are useful for preparing various types of medical articles that come into contact with blood.

REFERENCES:
patent: 3511684 (1970-05-01), Huffaker
patent: 3625745 (1971-12-01), Wright et al.
patent: 3634123 (1972-01-01), Eriksson et al.
patent: 3639213 (1972-02-01), Ginger et al.
patent: 3673612 (1972-07-01), Merrill et al.
patent: 3865615 (1975-02-01), Manly
patent: 4055635 (1977-10-01), Green et al.
Kunihiko, T., Immobilized Fibrin-Dissolving Enzyme For Prosthetics, Chemical Abstracts, vol. 86, 5/30/77 (161349m).
Zaborsky, O., Immobilized Enzymes, CRC Press, Cleveland, Ohio, 1973 (pp. 146-147).

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