Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-07-27
1997-07-22
Walsh, Stephen
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
43825233, 4383201, 536 235, C12N 1527
Patent
active
056502974
ABSTRACT:
This invention relates to a biologically active recombinant human M-CSF obtained by expressing a human M-CSF gene coding for the amino acid sequence of the formula (1) in its entirety or devoid of a portion thereof; a process for preparing the recombinant human M-CSF; an expression plasmid containing the human M-CSF gene defined above; and a transformant haboring the above expression plasmid.
REFERENCES:
patent: 4675291 (1987-06-01), Yamamura et al.
patent: 4677063 (1987-06-01), Mark et al.
patent: 4847201 (1989-07-01), Kaswasaki et al.
patent: 4868119 (1989-09-01), Clark et al.
patent: 4879227 (1989-11-01), Clark et al.
patent: 4929700 (1990-05-01), Halenbeck et al.
patent: 5026839 (1991-06-01), Moscatelli et al.
"Amino-terminal Region of Human Macrophage . . . Human M-CSF", by M. Takahashi et al., vol. 161, No. 2, Jun. 15, 1989, Biochemical and Biophysical Research Communications, pp. 892-901.
"Human CSF-1: Molecular Cloning and Expression . . . Urinary Protein", by G. Wong et al., vol. 235, Mar. 20, 1987, Science, pp. 1504-1508.
Jour. of Bacteriology, Aug. 1980, pp. 971-980, vol. 143, No. 2, "In Vitro Gene Fusions that join an Enzymatically Active .beta.-Galactosidase Segment to Amino-Terminal Fragments . . . Signals", Casadaban et al.
Science, vol. 220, p. 1053, 3 Jun. 1983, "A Parathyroid Hormone Inhibitor in vivo: Design and Biological Evaluation of a Hormone Analog", Horiuchi et al.
Biochem. & Biophys. Res. Comm., vol. 182, No. 1, 1992, pp. 70-77, "A Heterozygous Mutation (the Codon for Ser .sup.447 .fwdarw.a Stop Codon) in Lipoprotein Lipase Contributes . . . Hyperlipidemia", Kobayashi et al.
Peptides:Chemistry and Biology "Naturally Occurring Active Peptides from Anterior Pituitary and Gonads", Choh Hao Li, 6th Pierce Award Lecture, pp. 3-12, 1988.
Biochem. J. (1989) 259, 665-671, "A Key Functional Role for the Insulin-Like Growth Factor I N-Terminal Pentapeptide", Bagley et al.
Proc. Natl. Acad. Sci., vol. 86, pp. 3992-3996, Jun. 1989, "A Five-Residue Sequence Near the Carboxyl terminus of the Polytopic Membrane Protein Lac Permease . . . within the Membrane", Roepe et al.
The Jour. of Biological Chem., vol. 264, No. 21, pp. 12179-12186, 1989, "Amino Terminus is essential to the Structural Integrity of Recombinant Human Interferon-.gamma.", Hogrefe et al.
Protein Engineering, vol. 4, No. 3, pp. 335-341, 1991, "The Carboxyl-Terminal Region of Human Interferon .gamma. is Important for Biological Activity: Mutagenic and NMR Analysis", Lundell et al.
Protein Engineering, vol. 4, No. 4, pp. 385-389, 1991, "Structural and Functional Domains in Human Tumor Necrosis Factors", Cynthia R. Goh and Alan G. Porter.
The Jour. of Biological Chem., vol. 262, No. 12, pp. 5723-5731, 1987, "Structure-Function Analysis of Human Interleukin-2", Grace Ju et al.
J. Biochem., vol. 104, No. 5, 837-840, 1988, "Site-Specific Mutagenesis of the Human Interleukin-1.beta. Gene: The Role of Arginine Residue at the N-Terminal Region", Kamogashira et al.
Schoner et al., PWAS, vol. 81, p. 5403, 1984.
Ghrayeb et al., Embo J., vol. 3, p. 2437, 1984.
Takahashi et al. "Amino-Terminal . . . Of Human M-CSF" BBRC 161, 892 1989.
Cerretti et al., Molecular Immunology 25, 761, 1988 "Human Macrophage-Colony Stimulating Factor: Alternative RNA and Protein Processing From A Single Gene".
Cosman et al., Behring Inst. Mitt. 83, 15, 1988 "Human Macrophage Colony Stimulating Factor (M-CSF): Alternate RNA Splicing Generates Three Different Proteins That Are . . . ".
Heard et al., Oncogene Res. 1, 324, 1987 "Synthesis, Post-Translational Processing, and Autocrine Transforming Activity of a . . . ".
Rehenmier et al, Mol Cell Biol 8(11) 1988, pp. 5026-5034.
Mances, Mol Cell. Biol 8(11) 1988, pp. 5035-5039.
Science, vol. 230, 291-296, Oct. 18, 1985.
Science, vol. 235, 1504-1508, Mar. 20, 1987.
The EMBO Journal, vol. 6, No. 9, 2693-2698, 1987.
Kawasaki, E.S. et al. "Molecular Cloning of a Complementary DNA Encoding Macrophage Specific Colony-Stimulating Factor (CSF-1)", Science, vol. 230, pp. 291-296, 1985.
Saito, Y. et al. "Direct Expression of a Synthetic Somatomedin C Gene in Escherichia coli by Use of a Two-Cistron System", J. Biochem, vol. 101, pp. 1281-1288, 1987.
Ladner, M.B. et al., "Human CSF-1: gene structure and alternative splicing of MRNA precursors," The EMBO Journal, vol. 6, No. 9, pp. 2693-2698, 1987.
Hirai Yoshikatsu
Hirato Tohru
Hong Yeong-Man
Kouno Naomi
Nakai Satoru
Otsuka Pharmaceutical Co. Ltd.
Teng Sally P.
Walsh Stephen
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