Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-05
1997-07-22
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
530399, G01N 3353
Patent
active
056502850
ABSTRACT:
The present invention relates, in general, to a human CRIPTO-related gene. In particular, the present invention relates to a DNA segment encoding a human CRIPTO-related gene; polypeptides encoded by said DNA segment; recombinant DNA molecules containing the DNA segment; cells containing the recombinant DNA molecule; a method of producing a human CRIPTO-related polypeptide; a DNA segment encoding a genomic clone of the human CRIPTO gene (CR-1); antibodies specific to CR-3; and a method of measuring the amount of CR-3 in a sample.
REFERENCES:
patent: 5256643 (1993-10-01), Perisco
Ciccodicola, A et al; "Molecular characterization of a gene of the `EGF family` expressed in undifferentiated human NTERA2 teratocarcinoma cells.," The EMBO Journal, vol. 8, No. 7, pp. 1987-1991, (1989).
Dono, R. et al, Am. J. Human Genetics (USA) Sep. 1991, vol. 49, (3) pp. 555-565, "Isolation & Characterization of the CRIPTO Autosomal Gene and Its X-linked Related Sequence" (abstract).
Ciccodicola, Alfredo, et al. (1989) "Molecular characterization of a gene of the `EGF family` expressed in undifferentiated human NTERA2 teratocarcinoma cells", The EMBO Journal, 8:1987-1991.
Dono, Rosanna, et al. (1991) "Isolation and Characerization of the CRIPTO Autosomal Gene and Its X-linked Related Sequence", Am. J. Hum. Genet, 49:555-565.
Wallace, R. Bruce, et al. (1987) "Oligonucleotide Probes for the Screening of Recombinant DNA Libraries", Methods in Enzymology, 152:432-442.
Persica Maria G.
Salomon David S.
Housel James C.
Portner Ginny Allen
The United States of America as represented by the Department of
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