Method of preparation of 3-methylenecephams

Details Method of preparation of 3-methylenecephams Method of preparation of 3-methylenecephams

1977-05-13

1979-06-26

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602393R, 260307H, 26037637, 260376S, 2603323H, 546208, 546187, 546209, 546210, C07D20508, C07D40312

Patent

active

041592662

ABSTRACT:
Penicillin sulfoxide derived azetidinone sulfinyl chlorides and related sulfinic acid derivatives are cyclized to 3-methylenecephams by reaction with Friedel-Crafts catalysts or metathetic cation forming agents.

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