Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1995-06-07
1997-10-14
Prior, Kimberly J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514655, 514654, 514646, 564512, 564367, A61K 3113, A61K 31135, C07C21113, C07C21127
Patent
active
056773510
ABSTRACT:
Polyamines having the formula: ##STR1## wherein R.sub.1 and R.sub.2 are alkyl, aralkyl or aryl having up to 10 carbon atoms; and
a and b may be the same or different and are integers from 1 to 8; or a salt thereof with a pharmaceutically acceptable acid. Anti-neoplastic, anti-diarrheal, anti-peristaltic, gastrointestinal anti-spasmodic, anti-viral, anti-retroviral, anti-psoriasis and insecticidal compositions comprising biologically effective amounts of the above-described amines and biologically acceptable carriers therefor are also disclosed, as well as methods of treatment, administration or application of biologically effective amounts of the polyamines of the invention. Also disclosed are methods for preparing the polyamines of the invention.
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patent: 5217964 (1993-06-01), Edwards et al.
patent: 5434145 (1995-07-01), Edwards et al.
Weinstork et al, "Synthesis of New Polyamines Derivatives for Cancer Chemotherapeutic Studies", Journal of Pharm. Sciences, vol. 70, No. 8 (1981).
Clarke Dennis P.
Lambkin Deborah
Prior Kimberly J.
University of Florida Research Foundation Inc.
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