Substituted amine derivatives, their production and use

Details Substituted amine derivatives, their production and use Substituted amine derivatives, their production and use

1989-12-22

1991-01-22

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514211, 514212, 514247, 514248, 514249, 514255, 514256, 514259, 514307, 514311, 514331, 514357, 514365, 514372, 514374, 514378, 514385, 514396, 514408, 514412, 514419, 514427, 514431, 514433, 514436, 514438, 514439, 514451, 514452, 514471, 514483, 5142225, 5142275, 5142278, 5142352, 5142358, 5142368, 5142378, 540544, 540575, 540610, 544 581, 544160, 544168, 544224, 544235, 544238, 544242, 544283, 544337, 544353, 544373, 544400, 544405, 546147, 546165, 546175, 546247, 546331, 546335, 548204, 548248, 548325,

Patent

active

049871307

ABSTRACT:
Substituted amino derivatives represented by the formula: ##STR1## wherein R.sup.1 and R.sup.2 each stand for an acyclic hydrocarbon residue or an alicyclic hydrocarbon residue; R.sup.3 and R.sup.4 each stand for hydrogen or a hydrocarbon residue optionally containing hetero-atom(s); A stands for a carbon chain having two or more carbon atoms optionally containing ether linkage or sulfide linkage, which may be substituted and which may per se form a ring; X.sup.1 and X.sup.2 each stand for oxygen atom or sulfur atom; and Y stands for amino group or an organic residue bonded through nitrogen atom, which may form a ring by combining with a carbon atom constituting A; and their salts have anti-arrhythmic activity and are useful for prevention and treatment of a variety of arrhythmias.

REFERENCES:
patent: 3285960 (1966-11-01), Halverstadt
patent: 3723502 (1973-03-01), Pifferi

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