Azetidinone intermediates to carbacephalosporins and process

Details Azetidinone intermediates to carbacephalosporins and process Azetidinone intermediates to carbacephalosporins and process

1993-08-09

1995-09-26

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540364, C07D205085, C07D46300

Patent

active

054535034

ABSTRACT:
7.beta.-Amino-3-hydroxy-1-carba(1-dethia)-3-cephem-4-carboxylic acid esters are provided via cyclization of cis-3-(substituted amino)-1-(2-substituted 2-oxoethyl)-4-substituted azetidinones. The 7.beta.-amino-3-hydroxy-1-carba(1-dethia)-3-cephem-4-carboxylic acid esters are useful chiral intermediates to .beta.-lactam antibiotics.

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