Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-o

Details Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-o Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-o

1983-03-16

1986-02-18

Lesmes, George F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544117, C07D48704, C07D41306, A61K 31505, A61K 2700

Patent

active

045714231

ABSTRACT:
7-Deazapurine derivatives of the formula (I): ##STR1## (R.sup.1 is an acyl group; each of R.sup.2 and R.sup.3 is an alkyl, alkenyl or aralkyl group of alternatively R.sup.2 and R.sup.3, taken together with the adjacent nitrogen atom, form a cyclic amino group, and each of said alkyl group, alkenyl group, aralkyl group and cyclic amino group has a methylene group in .alpha.-position) and salts thereof are of value as intermediates for the production of antitumor agents, biological reagents, etc.

REFERENCES:
patent: 4435569 (1984-03-01), Nishimura et al.
March, J., "Advanced Organic Chemistry", pp. 820-823, McGraw-Hill Book Co., 2nd ed., (1977).
Duffy, T. D., et al., J. Chem. Soc. Perkin Trans. I, (16), pp. 1921-1929, (1974).
Seela, F., et al., Chem. Ber., 110, 1462-1469, (1977).

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