Phenyl and lower alkyl substituted pyrrole-3-acrylonitriles

Details Phenyl and lower alkyl substituted pyrrole-3-acrylonitriles Phenyl and lower alkyl substituted pyrrole-3-acrylonitriles

1979-09-17

1981-06-16

Sutto, Anton H.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D207337

Patent

active

042737133

ABSTRACT:
2,4,5,6-Tetrahydrocyclopenta[c]pyrrole-4-carboxamide and 4-thiocarboxamide derivatives useful as anti-secretory and anti-ulcer agents are prepared by hydrolysis of thiohydrolysis of the corresponding 2,4,5,6-tetrahydrocyclopenta[c]pyrrole-4-carbonitriles or, in the case of the thiocarboxamides, by reaction of the 4-carboxamide with phosphorus pentasulfide.

REFERENCES:
patent: 4008250 (1977-02-01), Bell et al.
patent: 4098797 (1978-07-01), Bell et al.

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