Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1979-07-23
1981-06-16
Berch, Mark L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
560148, 2602452T, C07D20508, C07D48704
Patent
active
042737095
ABSTRACT:
Disclosed is a process for the total synthesis of thienamycin from 4-allylazetidinone (IIIa) via ##STR1## L-aspartic acid (III): ##STR2## R.dbd.H, blocking group or salt cation.
REFERENCES:
patent: 4210661 (1980-07-01), Ponsford et al.
patent: 4223038 (1980-09-01), Smale
Durst, et al., J. Amer. Chem. Soc. 94, 9261 (1972).
Christensen Burton G.
Ratcliffe Ronald W.
Salzmann Thomas N.
Arno James A.
Berch Mark L.
Merck & Co. , Inc.
Pfeiffer Hesna J.
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