Preparation of benzo[b]thiophenes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549 44, 549 48, 549 49, 549 51, 549 57, 549 58, 568433, C07D33354

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052928942

ABSTRACT:
A process for the preparation of benzo[b]thiophenes of the general formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 independently denote hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, nitro, cyano, halo, C.sub.1 -C.sub.4 alkylcarbonyl, benzoyl, C.sub.1 -C.sub.4 alkylcarbonylamino, benzoylamino,N-(C.sub.1 -C.sub.4 alkyl)phenylamino, C.sub.1 -C.sub.4 alkoxycarbonyl, C.sub.1 -C.sub.4 alkylsulfonyl, phenylsulfonyl, aminosulfonyl, aminocarbonyl, C.sub.1 -C.sub.4 phenylalkyl and nitrobenzyl or R.sup.1 +R.sup.2 or R.sup.2 +R.sup.3 or R.sup.3 +R.sup.4 denote a butadienediyl chain optionally substituted by R.sup.1 to R.sup.4, in which

REFERENCES:
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A. R. Katritzky et al Adv. Heterocyclic Chemistry, 11, 206-239 (1970).
B. D. Tilak, Proc. Indian Academy of Sciences: 32A, 390-395 (1950).
Collin et al Ullmann's Encyclopedia D. Tech Chem. vol. 23, pp. 217-225, 4th Edition (1982).
O. DeLucchi, et al. J. Chem Soc, Chem: Commun., pp. 513-514 (1984).
T. Greene, "Protective Groups in Organic Synthesis", pp. 114-121 John Wiley & Sons, New York (1981).

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