Microelectronic axon processor

Details Microelectronic axon processor Microelectronic axon processor

1986-02-06

1986-12-30

Kamm, William E.

Surgery

Truss

Pad

A61B 1900

Patent

active

046321160

ABSTRACT:
Normal nerve function is restored across severed ends of a nerve fascicle by inserting between the severed ends a laminated chip perforated with an array of holes each sized to accommodate approximately one axon and each containing at least two electrically conductive regions in ohmic contact with the inner surface of the hole at discrete locations along the axial direction of the hole. Proximal axon segments are permitted to propagate through the holes to join distal segments in random fashion and to be in contact with each of the two electrical contacts. Each contact is part of a circuit pattern capable of monitoring impulses, applying blocking potentials and placing selected pairs of proximal and distal axon segments in electrical contact such that nerve impulses can be routed as desired to restore normal nerve impulse communication and hence nerve function.

REFERENCES:
patent: 3916905 (1975-11-01), Kuhn
patent: 4026300 (1977-05-01), DeLuca et al.
patent: 4306561 (1981-12-01), De Medinaceli
D. L. Jewett et al, Nerve Repair and Regeneration Its Clinical and Experimental Basis, .COPYRGT.1980, The C. V. Mosby Company, St. Louis, Toronto, London, pp. 105-114.
G. E. Loeb et al, "Analysis and Microelectronic Design of Tubular Electrode Arrays Intended for Chronic Multiple Single Unit Recording From Captured Nerve Fibers", Med & Biol Eng & Comput, Mar. 1977, vol. 15, pp. 195-201.
Mannard, "Regeneration Electrode Units: Implants for Recording from Single Peripheral Nerve Fibers in Freely Moving Animals", Science, Feb. 1974, vol. 18, pp. 547-549.
R. Llings et al, M. L. Phillips, Editor, "Implantable Monolithic Wafer Recording Electrodes for Neurophysiology", Brain Unit Activity During Behavior, .COPYRGT.1973, Charles C. Thomas Springfield, Ill., pp. 105-111.

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