Process for the production of 6-D-.alpha.-amino-p-hydroxyphenyla

Details Process for the production of 6-D-.alpha.-amino-p-hydroxyphenyla Process for the production of 6-D-.alpha.-amino-p-hydroxyphenyla

1980-03-24

1982-01-12

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

560 39, C07D49912

Patent

active

043104606

ABSTRACT:
Process for the production of 6-D-.alpha.-amino-p-hydroxyphenylacetamido penicillanic acid which is a potent antibiotic also known generically as amoxicillin. According to the process there is reacted a boron derivative of 6-APA with an acylating agent derived from the D(-)-p-hydroxyphenylglycine, in dimethylformamide or in dimethylsulfoxide in admixture with methylene chloride or chloroform, hydrolyzing and then removing the enaminic group.

REFERENCES:
patent: 3980637 (1976-09-01), Grossman et al.
patent: 4127571 (1978-11-01), Broggi et al.

Affiliated with

Also associated with

Rating

Process for the production of 6-D-.alpha.-amino-p-hydroxyphenyla does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of 6-D-.alpha.-amino-p-hydroxyphenyla, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of 6-D-.alpha.-amino-p-hydroxyphenyla will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1540497