Analgesic substituted-1-aminoalkylamino-4-aryloxypiperidines

Details Analgesic substituted-1-aminoalkylamino-4-aryloxypiperidines Analgesic substituted-1-aminoalkylamino-4-aryloxypiperidines

1984-04-13

1985-05-21

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514327, 546207, 546221, 549451, A61K 31445, C07D21146

Patent

active

045187134

ABSTRACT:
There are described analgesic substituted-1-aminoalkylamino-4-aryloxypiperidines of the formula ##STR1## where X is hydrogen, loweralkyl, CF.sub.3, acetyl or halogen; n is 1 or 2; R.sub.1 is H.sub.2 or oxygen; R.sub.2 is H, loweralkyl or benzyl; and R.sub.3 is oxygen or --OCH.sub.2 CH.sub.2 O--, which are useful as analgesic agents and intermediate compounds therefor.

REFERENCES:
patent: 3743645 (1973-07-01), Helsley
patent: 3869459 (1975-03-01), Milkowski et al.

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