Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-24
1995-04-11
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514331, 546231, 546247, A61K 31445, C07D21114
Patent
active
054058546
ABSTRACT:
Sulfonamidocarboxamides of the formula ##STR1## wherein A, M, Q, X and Y have the significance given in the description, as well as hydrates, solvates and salts thereof, which inhibit thrombin-induced blood platelet aggregation and clotting of fibrinogen in plasma, as described. The compounds of formula I can be prepared by amidination of a cyclic amino group standing for grouping X or by C(O)N(Q) amide formation.
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Ackermann Jean
Banner David
Gubernator Klaus
Hilpert Kurt
Schmid Gerard
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
Lee Mary C.
McKane Joseph K.
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