Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-13
1995-04-11
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514305, 514312, 514361, 546112, 546133, 546277, 548128, C07D41314, A61K 3133
Patent
active
054058538
ABSTRACT:
A class of novel thiadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring system, and substituted on the other ring carbon atom with a substituent of low lipophilicity, or a hydrocarbon substituent; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses, and are also of benefit in the treatment of severe painful conditions.
REFERENCES:
patent: 3912495 (1975-10-01), Moser et al.
patent: 4301069 (1981-11-01), Weaver et al.
patent: 4645525 (1987-02-01), Forster et al.
patent: 4968691 (1990-11-01), Orlek
Zbirovsky, M., et al Chem. Abs. 76 (1972) 113135k.
Potts, Comprehensive Meterocyclic Chemistry pp. 492-501 (1989).
Baker Raymond
MacLeod Angus M.
Merchant Kevin
Saunders John
DiPrima Joseph F.
Gerstl Robert
Merck Sharpe & Dohme Ltd.
North Robert J.
Winokur Melvin
LandOfFree
Thiadiazoles useful in the treatment of senile dementia does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Thiadiazoles useful in the treatment of senile dementia, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thiadiazoles useful in the treatment of senile dementia will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1538725