Anti-neoplastic, anti-viral and ribonucleotide reductase activit

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514375, 514408, 514411, 514422, 514423, A01N 4376, A61K 3142

Patent

active

052927750

ABSTRACT:
A method for treating a human or non-human animal afflicted with malignant cells sensitive to parabactin or a pharmaceutically acceptable salt or complex thereof comprising administering to the animal an amount of parabactin effective to inhibit the proliferation of the malignant cells.

REFERENCES:
Chemical Abstracts 101(11)83660t "Antineoplastic and antiheptis activity of spermidine catecholamide iron chelators" Bergeron et al. (1986).
Chemical Abstracts 104(25)218731b "Effects of the Vibrio Cholerae siderophore vibriobactin on the growth characteristics of L1210 cells" Bergeron et al. (1986).
Chemical Abstracts 105(5) 42565e "Synthesis of parabactin and homologs" Bergeron et al. (1986).

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