Technetium-99m labeled somatostatin-derived peptides for imaging

Details Technetium-99m labeled somatostatin-derived peptides for imaging Technetium-99m labeled somatostatin-derived peptides for imaging

1992-11-17

1995-04-11

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

A61K 4900

Patent

active

054055970

ABSTRACT:
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention specifically provides somatostatin, somatostatin derivatives, somatostatin analogues or peptides that bind to the somatostatin receptor and contain at least 2 cysteine residues that form a disulfide or wherein the disulfide is reduced to the sulfhydryl form that are labeled with technetium-99m and that can be targeted to specific sites within a mammalian body for imaging.

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