Stable erythropoietin preparation and process for formulating th

Details Stable erythropoietin preparation and process for formulating th Stable erythropoietin preparation and process for formulating th

1985-10-03

1989-02-21

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514970, 530395, A61K 3702

Patent

active

048065242

ABSTRACT:
A stable erythropoietin preparation and a process for formulating the same are disclosed.
Erythropoietin is useful in the treatment or diagnosis of anemia, but it is an instable substance. In order to provide a stable erythropoietin preparation, it is formulated with one or more stabilizers selected from the group consisting of polyethylene glycols, proteins, sugars, amino acids, inorganic salts, organic salts and sulfur-containing reducing agents.

REFERENCES:
Krystal et al., British Journal of Haemotology; vol. 58, No. 3, Nov. 1984, 533-546.
Krystal et al., cited in Chem. Abstracts vol. 102:17774c, 1985.

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