2-Pyrazinyl-trifluoromethylimidazoles and a method for their pre

Details 2-Pyrazinyl-trifluoromethylimidazoles and a method for their pre 2-Pyrazinyl-trifluoromethylimidazoles and a method for their pre

1975-09-05

1977-06-28

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260288CE, 260296R, 2603068R, 260309, 260310R, C07D24104, C07D40304

Patent

active

040325229

ABSTRACT:
4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammonia. The 4(5)-trifluoromethylimidazoles are useful as anti-gout and anti-hyperuricemic agents.

REFERENCES:
patent: 3786061 (1974-01-01), Novello et al.
patent: 3818014 (1974-06-01), Baldwin et al.
Poyser et al. Chemical Abstracts, vol. 74, 100,048t, (1971).

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