Arylalkyl diazinones

Details Arylalkyl diazinones Arylalkyl diazinones

1996-09-13

1999-01-12

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142292, 514252, 544 8, 544 66, 544240, A61K 3154, A61K 31535, C07D28516, C07D27300

Patent

active

058590080

ABSTRACT:
Arylalkyl diazinone derivatives of the formula I ##STR1## and their physiologically acceptable salts, in which
R.sup.1, R.sup.2, R.sup.3, R.sup.4, B, Q and X have the meanings indicated in claim 1, exhibit phosphodiesterase IV inhibition and can be employed for the treatment of inflammatory processes and also of allergies, asthma and autoimmune disorders.

REFERENCES:
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patent: 5039675 (1991-08-01), Morsdorf et al.
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patent: 5344925 (1994-09-01), Goulet et al.
patent: 5434149 (1995-07-01), Jonas et al.
patent: 5454149 (1995-10-01), Jonas et al.
Klemm et al., "Effect of rolipram in a murine model of acute inflammation. . . ", Eur. J. of Pharmacol., 281 (1995) pp. 69-74.

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