Device including a biologically active substance immobilized on

Details Device including a biologically active substance immobilized on Device including a biologically active substance immobilized on

1996-07-19

1999-01-12

Knode, Marian C.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

436805, 436806, 422 57, 435 5, 435176, 435291, 435 14, 427508, G01N 33551, G01N 2100, C12Q 170, C12N 1114

Patent

active

058588027

ABSTRACT:
The invention relates to a device including a substrate and at least one biologically active substance bound to at least a part of the surface of this substrate, which is obtained by simultaneous or sequential reaction of said substrate and of said substance with a bifunctional coupling agent in which one of the functional groups is capable of being photoactivated and generates carbenes and is used to bind the coupling agent to the inorganic substrate and the other functional group is used to bind the coupling agent to the biologically active substance, in which said substrate is a covalent inorganic nitride.

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Lolliard et al., Bioconjugate Chem. 4:528-536, 1993.

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