Method of treating lung disease with uridine triphosphates

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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424 46, 514 50, 514 51, 514255, A61K 3100, A61L 904

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active

052924980

ABSTRACT:
A method of hydrating mucous secretions in the lungs of a subject in need of such treatment is disclosed. The method comprises administering to the lungs of the subject a uridine triphosphate such as uridine 5'-triphosphate (UTP) or uridine 5'-O-(3-thiotriphosphate) (UTP.gamma.S) in an amount effective to hydrate lung mucous secretions. The method is useful for treating patients aflicted with cystic fibrosis. Pharmaceutical formulations and methods of making the same are also disclosed.

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