Animal model for hepatitis virus infection

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition

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424 91, 4351723, 800 2, A61K 4900, C12N 1500, G01N 3100

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active

058583289

ABSTRACT:
A non-human chimeric animal is obtained by transplanting a non-human mammal host having a T cell deficiency with a human liver tissue preparation or with a liver tissue preparation from a non-human animal capable of being infected by the hepatitis virus (HV). The non-human chimeric animal is useful as an HV model for evaluating anti-HV therapy and prophylaxis.

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