Sialic acid derivative with active ester groups

Details Sialic acid derivative with active ester groups Sialic acid derivative with active ester groups

1989-11-27

1991-12-31

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 41, 536 172, 536 175, 536119, C07H 506, C07H 1520

Patent

active

050773976

ABSTRACT:
Sialic acid derivative with active ester groups expressed with the formula [I] ##STR1## Where R.sup.1 denotes hydrogen or an acetyl group, R.sup.2 denotes hydrogen or a lower alkyl group, R.sup.3 denotes C.sub.2 H.sub.4, C.sub.3 H.sub.6 or C.sub.2 H.sub.2, R.sup.4 denotes an hydroxyl group, the residue left after removing hydrogen from the alcohol portion of the active ester or alkyloxycarbonyloxy group, AC denotes an acetyl group, Ph denotes an phenyl group, and X denotes oxygen or sulfur. This sialic acid derivative has high reactivity because it has active ester groups in the molecules and can be used as a raw material or intermediate for synthesis of various sialic acid derivatives.

REFERENCES:
patent: 4914035 (1990-04-01), Hasegawa et al.
patent: 4918177 (1990-04-01), Yoshimura et al.
patent: 4963653 (1990-10-01), Nagai et al.
Privalova et al.; Izv. Akad. Nauk SSSR, Ser. Khim. 12:2785-2792 (1969).
Shimizu et al.; Carbohydrate Research, 166:314-316 (1987).

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