Process for the preparation of L-tryptophan

Details Process for the preparation of L-tryptophan Process for the preparation of L-tryptophan

1985-02-15

1988-05-03

Tarcza, John E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435253, 435843, C12P 1322, C12N 120, C12R 115

Patent

active

047420073

ABSTRACT:
L-tryptophan can be prepared in good yield by a fermentation process which comprises culturing a novel L-tryptophan-producing microorganism of the genus Corynebacterium, which is resistant to at least one member selected from glyphosate [N-phosphonomethyl glycine], paraquat [1,1'-dimethyl-4,4'-bispyridinium] and derivatives thereof, and recovering L-tryptophan from the culture broth.

REFERENCES:
patent: 3594279 (1971-07-01), Nakayama et al.
patent: 4535060 (1985-08-01), Comai
Metzler, Biochemistry, 1977, pp. 850-855.
Comai et al., "An AroA Gene Product Confers Resistance to the Herbicide Glyphosate", Science, vol. 221, (Jul. 22, 1983), pp. 370-371.
Rogers et al., "Amplification of the aroA Gene from Escherichia coli Results in Tolerance to the Herbicide Glyphosate", Applied and Envir. Micro., vol. 46, No. 1, (Jul. 1983) pp. 37-43.
Japan, vol. 5, No. 164(C-76) (836), Oct. 21, 1981.
Japan, vol. 8, No. 236 (C-249) (1673), Oct. 30, 1984).

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