Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Patent
1995-05-24
1996-07-02
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
514 12, C12P 2102
Patent
active
055321445
ABSTRACT:
Pure peptide products, derived from either human glioma cell line U-105MG or human peripheral blood mononuclear leukocytes are provided; the products have a molecular mass of about 8,400 daltons, and the products exhibit optimal monocyte chemotactic activity at a concentration of 1 nM. Methods of treating infection and neoplasms in a human body with the peptide products are additionally provided, as well as pharmaceutical compositions for the peptide products.
REFERENCES:
patent: 4514387 (1985-04-01), Wissler
S. Cushing et al., Proc. Natl. Acad. Sci. USA, vol. 87, pp. 5134-5138, Jul. 1990.
Poncz et al., Blood, vol. 69, No. 1, pp. 219-223 (Jan. 1987).
Patent Abstracts of Japan, vol. 10, No. 71, (C-334) (2128), Mar. 1986, and JP-A-60-208 921 (Teijin), Apr. 1984.
Journal of Immunol., vol. 117, No. 5, Foon et al., Part 1, Nov. 1976.
Journal of Immunol., vol. 110, No. 3, Altman et al., Mar. 1973.
Van Damme et al., J. Exp. Med., 176, pp. 59-65 (1992).
Biochemical and Biophysical Research Communications, vol. 159, No. 1, 1989, pp. 249-255.
Valente et al., "Purification of a Monocyte Chemotactic Factor . . . ", Biochemistry, vol. 27. pp. 4162-4168 (1988).
Ramb et al., "Characterization of Human Lymphocyte Derived Chemotactic Factor," Molecular Immunology, vol. 20 (3), pp. 325-332 (1983).
T. Yoshimura et al., Federation of European Biochemical Societies, vol. 244, No. 2, pp. 487-493.
T. Yoshimura et al., The Journal of Immunology, vol. 142, No. 6, pp. 1956-1962, (Mar., 1989).
D. T. Graves et al., Science, vol. 245, pp. 1490-1493.
Webster et al "Inflammation" vol. 4 No. 3 (1980) pp. 261-269.
Nakajima "Polymer Molecular Weight" Advances in Chem. Series No. 5 pp. 99-107 Erzin Estor 1973.
Appella Ettore
Leonard Edward J.
Robinson Elizabeth A.
Yoshimura Teizo
Lilling Herbert J.
The United States of America as represented by the Department of
LandOfFree
Process for preparing human derived monocyte attracting purified does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for preparing human derived monocyte attracting purified, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing human derived monocyte attracting purified will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1505861