Plasmodium vivax blood stage antigens, PvESP-1, antibodies, and

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 792, 435 793, 435 794, 435 795, 436518, 436524, 436528, 5303871, 5303881, G01N 3353, G01N 33543, G01N 33569, C07K 1620

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055321330

ABSTRACT:
This invention is directed to novel species-specific P. vivax malarial peptide antigens, PvESP-1 is a protein or fragments of the protein secreted into the plasma of a susceptible mammalian host after infection, and to monoclonal or polyclonal antibodies directed against this antigen. The peptide antigen, monoclonal antibodies, and/or polyclonal antibodies are utilized in assays used to diagnose malaria, as well as to determine whether Plasmodium vivax is the species responsible for the infection.

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