Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-07-28
1996-01-23
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514252, 514317, 514318, 514319, 514320, 514326, 514343, 514408, 514422, 514428, 544229, 544336, 546193, 546197, 548526, A61K 31445, C07D40506, C07D40512
Patent
active
054865271
ABSTRACT:
Selective muscarinic receptor antagonists of formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are both optionally substituted phenyl, the broken line is an optional bond, X is >COH--, >SiOH-- or CH-- when the double bond is absent or is >C.dbd. when the double bond is present, X being attached to a carbon atom of A, A is selected from certain piperidine and pyrrolidine groups, n is 1 to 3 and R.sup.3 is optionally substituted phenyl or thienyl, pyridyl or pyrazinyl.
REFERENCES:
patent: 4540780 (1985-09-01), Downs
patent: 5096890 (1992-03-01), Cross
patent: 5233053 (1993-08-01), Cross
Kalsner "Trends in autonomic pharmacology" Tayer & Francis pp. 17-19, 28-31 (1985).
Alker David
Cross Peter E.
Chang Ceila
Creagan B. Timothy
Holtrust Gezina
Pfizer Inc.
Richardson Peter C.
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