Process for the preparation of phenyl ketones

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568319, 568322, 568306, 260465D, 562460, 564329, C07C 4543

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active

044530129

ABSTRACT:
A process for the preparation of phenyl ketones, characterized in that, in a first stage, a halo- or trihalomethylbenzene is reacted with a trihalomethylated aliphatic or aromatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent, and in that, in a second stage, the resultant product is hydrolyzed. The products are used as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.

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