Process for making enamines

Details Process for making enamines Process for making enamines

1982-11-05

1984-06-05

Raymond, Richard

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544146, 544379, 546213, 548336, 548374, 548527, 549 79, C07D33320

Patent

active

044529791

ABSTRACT:
A process for preparing antiinflammatory enamines of the following formula ##STR1## wherein R is lower alkyl; R.sup.1 is selected from the group consisting of lower alkyl, benzyl, and N,N-dimethylaminoethyl; or R and R.sup.1 are fused to form an optionally-substituted five- or six-membered heterocyclic ring; and X is hydrogen, methyl or halogen, comprising (a) reacting a 3,5-bis(t-butyl)-4- hydroxybenzoyl-substituted thiophene with a chlorine source selected from thionyl chloride and phosphorus pentachloride; and (b) reacting the resulting intermediate with an amine to provide the enamine.

REFERENCES:
patent: 4128664 (1978-12-01), Moore
patent: 4172082 (1979-10-01), Moore

Affiliated with

Also associated with

Rating

Process for making enamines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for making enamines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for making enamines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1498473