Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1983-08-05
1984-06-05
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544230, 544360, 544364, 544368, 544373, C07D41300, A61K 3141
Patent
active
044527993
ABSTRACT:
Disubstituted N,N-piperazinyl derivatives are disclosed wherein one substituent is benzisothiazol-3-yl or benzisoxazol-3-yl and the other is alkylene attached to heterocycles such as azaspiro[4.5]decanedione, dialkylglutarimide, thiazolidinedione and spirocyclopentylthiazolidinedione or butyrophenone-like groups. The compounds have psychotropic properties and 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]deca ne-7,9-dione is a typical embodiment having selective antipsychotic activity.
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Temple, Jr. Davis L.
Yevich Joseph P.
Daus Donald G.
Gibson S. A.
Mead Johnson & Company
Ryan Richard P.
Uloth Robert H.
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